The parish had grown to 100 members by about 1950. In 1951 Metropolitan Leonty blessed the newly purchased site at Massachusetts Avenue and Edmunds Street, our current location.

In 1955 after the death of Bishop Jonah (rector), Archpriest Arkady Moiseyev became Rector of St. Nicholas Church. Fr Moiseyev guided St. Nicholas through the building and dedication of our current facility. The edifice was completed in late 1962 and was dedicated as a National War Memorial Shrine in 1963.

Over the years St. Nicholas Cathedral has had many dedicated clergy serving our church. With the elevation of St. Nicholas to the Metropolitan's Cathedral, Fr Arkady Moiseyev became Dean and Fr Dmitry Grigorieff became Provost. In the early 1970s Fr Dmitry was very active in ensuring that there were regular English Liturgies. In 1986 Fr Dmitry was elevated to Dean of the Cathedral and Fr Constantine White became Associate Pastor. In February 1998 Fr Dmitry became Dean Emeritus and Fr Constantine was made Acting Dean. Later that year Father Constantine was installed as the Dean of the Cathedral.  Father Valery Shemchuk joined that Cathedral staff in an official capacity as Associate Pastor in early 2003 after having served several summers here as a Seminarian intern. 

St. Nicholas has always had a very active Choir. Mr. Nicholas Borodulia was the choir director from 1955 to 1985.  In 1996 Professor Serge Boldireff joined the choir and led it to a more visible role. The choir was proud to participate in Metropolitan HERMAN’s Enthronement in 2002 as well as many visits from hierarchs, such as the Catholicos-Patriarch of Georgia, in the past several years.  In 2003, the choir released its latest CD "This is the Day", available at the Cathedral Bookstore or through the Orthodox Christian Publications Center.  In June of 2005, the Cathedral welcomed Ken Kasovac as the new Music Director.